In a limited number of cases it is possible to predict from the equation for the reaction whether it will be exothermic or endothermic.
Separating particles that have an attraction for one another is
endothermic.
Bringing particles that have an attraction for one another
closer together is
exothermic.
Processes are
endothermic in one direction and
exothermic in the opposite direction.
Thus the phase changes below are endothermic in the forward direction as interparticle forces are being disrupted. They are exothermic in the reverse direction as the particles are being brought closer together.
| solid | endothermic
 exothermic | liquid | endothermic
 exothermic | gas |
Separation of charge requires energy and is
endothermic.
Neutralizing charge or
dispersing charge over a bigger volume releases energy and is
exothermic.
- First ionization energy:
Na(g)
Na+(g) + e– endothermic
- Lattice energy:
Na+(g) + Cl–(g)
NaCl(s) exothermic
- Hydration energy:
Na+(g) + 6H2O
Na(H2O)6+ exothermic